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Porcine Circovirus type 2 (PCV-2) infection is almost ubiquitous. PDNS (Porcine Dermatitis and Nephropathy Syndrome) may develop in older pigs where the antibody response has been weak and high levels of virus are present. It is associated with haemorrhages in many organs and has a high mortality rate. The gross lesions on the skin are usually obvious. There is usually gross enlargement of the kidneys which are pale with a granular surface and appear to be petechiated, and haemorrhages can be found on the serous surfaces and in the swollen lymph nodes. The gross lesions must be differentiated from both Swine Fevers.